Isis Pharmaceuticals

Isis Pharmaceuticals, Janssen collaborate

Wednesday, January 7, 2015

Isis Pharmaceuticals, based in Carlsbad, Calif., has entered into a global collaboration with Janssen Biotech to discover and develop antisense drugs to treat autoimmune disorders of the gastrointestinal (GI) tract. The collaboration brings together Isis’ RNA-targeted technology platform and the expertise of Janssen in autoimmune disorders and therapeutic formulation to discover and develop antisense drugs that can be locally administered, including oral delivery, to treat autoimmune disorders in the GI tract.

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GSK pays Isis $7 million for ISIS-GSK3Rx milestones

Tuesday, October 8, 2013

GlaxoSmithKline (GSK) has added development candidate ISIS-GSK3Rx to its collaboration with Isis Pharmaceuticals. Isis earned $7 million in milestone payments associated with the advancement of this program. ISIS-GSK3Rx is an antisense drug designed to inhibit the production of an undisclosed target to treat a common viral infection. Isis will develop ISIS-GSK3Rx to phase II proof-of-concept, after which GSK has an exclusive option to in-license the program and further develop and commercialize the asset.

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Isis, AstraZeneca form strategic alliance on RNA therapeutics for cancer

Wednesday, December 12, 2012

Isis Pharmaceuticals of Carlsbad, Calif., and global biopharmaceutical company AstraZeneca have formed a strategic alliance for the discovery and development of novel generation antisense therapeutics against five cancer targets, which includes a license to develop and commercialize ISIS-STAT3Rx, a drug Isis is currently evaluating in an early clinical trial in patients with advanced lymphomas.

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Biogen Idec, Isis collaborate on antisense programs for neurological disorders

Monday, December 10, 2012

Weston, Mass.-based Biogen Idec and Isis Pharmaceuticals of Carlsbad, Calif., have entered into a global collaboration agreement to discover and develop antisense drugs against three undisclosed targets to treat neurological or neuromuscular disorders. Biogen Idec and Isis are already collaborating on antisense drugs to treat spinal muscular atrophy and myotonic dystrophy type 1 under previously established collaborations.

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